For the first time in the history of Uzbekistan

For the first time in the history of Uzbekistan, laparoscopic removal of liver metastases was performed at the Republican Oncology Center

For a long time, even with single metastases of colorectal cancer (CRT) in the liver, only symptomatic surgical interventions on the intestine in the form of superimposition of external fistulas or internal anastomoses were used. Resections of the liver for solitary colorectal and rectal cancer metastases performed both at once with the removal of the primary tumor and at a later date as they occur, are now becoming increasingly common. Surgical treatment of liver metastases is justified by the lack of other effective alternatives. Naturally, we are talking about operable metastases in the liver.

At primary treatment of patients, neglected forms of cancer (III-IV stages) are diagnosed in 71.4% of patients with colorectal cancer and 62.4% – with rectal cancer [1]. In total 20% of patients with colorectal cancer (CD) at the moment of diagnosis have remote metastases, approximately 25-30% of them have isolated liver metastases. The average life expectancy of patients with metastatic liver damage without specific treatment is less than 1 year, and in case of synchronous metastases – 4.5 months from the moment of diagnosis. With the development of science of oncology and surgery 5-year survival rate in patients with metastatic colorectal cancer has increased from 14% to 60% (data from Johns Hopkins University).

This case embodies the achievements at the Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology. The patient received specialized treatment in a combination of chemopreparations and targeting drugs, after conducting a tumor to resectable forms, performed a laparoscopic sigmoidectomy. Further, the patient was hospitalized to remove metastatic foci in the liver.

A group of surgeons headed by Mirzagaleb Nigmatovich Tillyashaykhov, the director of the center, successfully performed for the first time in the history of Uzbekistan laparoscopic liver resection for limited metastases (2 pcs, 3 and 8 segments, up to 4 cm) in the liver.

Unlike traditional or, as they say, open surgery, laparoscopic method has a number of advantages: small traumatism and short hospital stay of the patient (6-7 days), fast recovery after the operation, no painful feelings, and no postoperative scars.

The patient is successfully discharged home from the clinic for 4 days after surgery.

We congratulate oncologists of the country with the remarkable event and wish them success in their further work!

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